ENGINEERING
The key thing - which many established players will have done already anyway - is to unlock Dweller, Martuuk, Ryder and McQuinn and get them to at least G4. That'll let you unlock all the Colonia engineers if you want to later, without a return trip. Even if you don't think you'll do much engineering, they're all pretty quick unlocks for an established player.
Something to remember is that anything you can buy locally will be cheaper than transferring it (and you'll then have one in the bubble as well if you go back) - but that gets offset against extra time spent engineering it. And most things - with a bit of patience on stock on a few big core modules - can be bought locally nowadays.
So if you've built up decent material reserves, just fly out, build ships out here, engineer them up to G4 (and G5 where you have the materials to justify it), and transfer a few cheap G5 modules (utilities and weapons, for example) to finish them off. G4+experimental gives you well over 80% of the performance of a maxed G5 for a small fraction of the material cost, so you might find that easier.
Pinned blueprint selection you might well want to change from your normal bubble one - with everything so close, you don't really need to pin anything available locally. I'd recommend at the moment:
McQuinn: railgun
Ryder: missile or torpedo
Ishmaak: mines
Nemo: frags
Cheung: DSS or Sensors*
Tani: Power Plant*
Tah: any except collector, prospector or heat sink
Sarge: cannon, or maybe fuel transfer/hatchbreaker limpets
Jameson: DSS or Sensors* (whichever you didn't pin with Cheung)
Turner: Plasma Accelerator
Fortune: your favourite utility scanner (KWS or Cargo less available locally)
(All other bubble engineers are equalled or outclassed locally, so the pin is irrelevant)
* These blueprints are rapidly approaching G5 in Colonia and should be there in the next two months just at background research levels, so could be skipped.
When ranking up with a Colonia engineer for the first time, you will help everyone if you pick a module that isn't yet G5 to do this with. Hopefully you can find one you have a use for.
TECH BROKERS
If you want any tech broker modules, unlock them before you leave. We have tech brokers out here so you can buy anything you've already unlocked, but no suitable Guardian sites are known anywhere nearby, and most of the commodities needed for the human tech broker aren't available either (there are a few, but only a few)