Nah man, gankers would love that mega server structure where they could get their hands on you enmasse. If something like that were implemented, the ensuing PvE white knight massacre would look something like this:
I would very much like to see what would happen. There are quite a few examples of large animals or people taken out by fire ants, siafu, or africanized bees. I would like to see how those japanese hornets would do against africanized bees or the aggressive ants.
As far as the comparison between gankers and DW2 that is completely specious (not your statement Jason). The group of players were geared specifically for exploration not general purpose. Again, individual instances would not tolerate 40 players to mount any legit defense.