About half of the rage quit threads on the forum start with this.
A Python is the first ship where the cost of a rebuy becomes pretty high. A combat fitted Python is formidable, but still has weaknesses - its agility being the main one. But a multi-purpose build, or worse a trade build, is never going to do well against elite NPC wings. A Python doesn't usually have the speed to low wake out of an interdiction, so tactics that worked for a smaller ship don't always apply to the Python.
Finding interdiction painful too , been running around with mats in a Python (upgraded, a bit ) doing long haul runs, kept my Combat rank low at 45% expert , so the NPC aren't high , but what's getting me into trouble more is nearly every 3rd interdiction is an FSD failure , WHY is my FSD failing , was working fine minute ago, :O still submitting straight away.
Have heard its that mini game of the Blue/Red but never bother with that anymore
Yes interdiction need some work , NPC have to stop cheating ,their FSD have to cool down too, but with the next Update , storage of Mats means, hopefully less of these FSD failures close calls.