There are many things I still haven't seen in the Milky Way, and seeing them "by accident", like the first time I got interdicted by a Thargoid, is one of the things making ED so special. On the other hand, there are probably many things you never get to see, unless you push yourself out of your comfort zone. I personally like core mining and I have a favorite Haz Res close to Jameson Mem that I go to when I feel the urge to annihilate. I probably spend 90% of my time in ED doing those two, but it's the extraordinary challenges you put yourself into that give you those "wow moments".Seconded!
Going off to the Guardian sites is quite a different experience to anything else. I was glad to have done it and got the ability to buy the FSD booster; I have yet to fit one to Hecla but it is only a matter of time before I get the urge to head out into the black again...
The Guardian sites in the dark, with the scary music, are very atmospheric.