I've been using a hotas setup exclusively for my entire gametime I have in elite and I can say that yes, it seems easier for MnK users to aim in FAoff with relative mouse but no, the difference is barely noticeable for me.
There are advantages and disadvantages for every input setup. It would be weird if it wouldn't as different setups would then imply absolute equality in difficulty of use for all areas.
Then the next question is, what is the purpose of this thread? I fail to understand the intention behind it when stating something that is correct to some degree but doesn't come with an appeal or something similar. As an informative post, it might be worth a read but then this is in general discussions.
So my reactions is something like: "Yes, and ...?"