I went a different way with my Thrustmaster T.Flight HOTAS controls but it works for me. The throttle controls velocity of course and the stick controls maneuvering but I've reconfigured a number of things to suit my style of play.
On the actual throttle element:
Thrust Up (maneuvering and station keeping): Joy 6
Thrust Down (maneuvering and station keeping): Joy 7
Boost: Joy 8
Primary Fire: Joy 5 so I have both throttle control and fire to hand for a moment's execution.
I also reconfigured the joystick itself so that the hat-switch now handles fine maneuvering thrusters for docking and precision station keeping.
Thrust Left (maneuvering and station keeping): Pov1-Left
Thrust Right (maneuvering and station keeping): Pov1-Right
Thrust Forward (maneuvering and station keeping): Pov1-Up
Thrust Back (maneuvering and station keeping): Pov1-Down
I'm aware that Pov1-Up (thrust forward) and Pov1-Down are the same as the throttle settings but when docking or maneuvering I like to have minute control of the ship for tricky maneuvering. It also helps when orientating for tricky ingress/egress tunnel execution.
I also remapped the Jettison Cargo to the PAUSE key for safety reasons, and the Cargo Scoop to the PAGE UP key as I was getting a bit too punchy when in threat-interaction situations. Silent Running has now been moved to SCRN LOCK and tapping INSERT deploys the Landing Gear.
I also choose to re-map the UI/GUI interface access for easier handling. Using the cursor keys to move around it (logically really) and the DELETE and END keys to scroll left and right between fields. Selection is done with ENTER.
Wing controls have also been relocated to the auxiliary keyboard so that wingmen can be access by simply selecting NUM 1, NUM 2 or NUM 3. Wing Target is now INS and Lock Wing Navigation is selected with NUM LOCK.
I'm sure you guys already know this, but have just discovered CTRL+ALT+G and having some fun with that. Other than the modifications mentioned here, my keyboard/mouse/joy layout is pretty much the same as the default system settings.