Urgh, that's rough.
Once it's loaded, take this advice:
1. Read the manual - it really is useful. Lots of little bits of info that make clear a lot of things that could go wrong when you're flying. Hopefully, you'll be able to avoid them.
2. Do the practice missions before you start for real - basic stuff like how to take off, how to land, how to travel between systems, basic combat. It's very useful knowing this stuff.
3. Rebind the following keys:
(a) Boost - make sure this is nowhere near your landing gear key. Once your landing gear is down, you shouldn't be able to boost, but I put in a landing override so my boost key does yaw left instead while landing gear is down, just in case. So many pilot accidents have occurred while boosting by accident inside stations.
(b) Jettison All Cargo - put this key somewhere else. Make it a combo (ctrl-something) to be safe. This is something you will almost never find yourself in a situation needing to do quickly. And it is a really, really bad thing to do by accident.
(c) Rotational Correction - this makes your ship automatically correct to match the rotation of a station once inside. You pretty much always want this to be on. Have a key for it, and know what it is, just in case it gets turned off somehow. It's annoying having to find the manual toggle for it in your ship systems.
4. Once you're in the real galaxy, never fly without your insurance buyback - Insurance is paid when you first buy your ship. However you still have to cover an excess if your ship blows up, which is about 5% of the ship's value, plus 5% of any modules you've put on it. You need to have this amount of money (preferably three times this amount actually) so if your ship blows up, you don't lose the whole thing - you can buy back a replacement ship with only 5% of its value, as the rest is covered by your insurance. You can see your current ship's buyback value right under how much money you have in the right hand systems menu. DO NOT TAKE OFF WITHOUT THIS MONEY. Or take off, but be prepared to lose everything if you blow up.
5. Do not fly without insurance.
6. Do not fly without insurance. Seriously, so much rage has occurred because of people flying without insurance.
7. Have fun flying around in the galaxy, welcome to Elite!