Yea, I too have now played ED with Vive, and granted its scale and immersion is great, it does not carry into the holistic ED experience I had on my three 2D monitors. Outside the naturally clearer visuals in 2D, the biggest hit for me in VR is lack of usability of my side panels which host browser based tool and apps such as Inara, EDDB, EDEngineer, and TCE. I use all these tools to complement a holistic ED experience, and in VR I lack that. Its a feeling of "what should I do now" in VR; where as, with all the tools, I can find meaning/purpose.
Last night, I flew a few hours in VR and switched among a few of my ships to see differences. Indeed, that is the best part, to see the differences VR offers over 2D relative to the experience in the chair (with room scale on, u can get up and walk around bridge too!). However, for meaningful gameplay, I find its not really fulfilling in VR as compared to all else available in the 2D space. I guess for players who do not use external apps and tools, you may not know what I am referring to... but those that do, likely do.
All in all, perhaps in the future as VR tools evolve and in VR apps/tools are available, it may bring it up to par. Though now for me, VR in ED is a fun 10 min "Wow!" factor, but for doing stuff in game, I find I need 2D.
Note though, I play RecRoom in VR and LOVE the paintball game and other offerings there strictly for VR! There i can spend hrs having fun in that type of VR experience, but in ED, i need more...