Hmm, I have a 40" 4K screen and I run it with no scaling. I use the built in windows shortcuts to move windows around (Win+Arrow Keys), meaning that for productivity I essentially have 4 1080p screens to work on.
I do sit fairly close to the screen though, which helps![]()
Swings and roundabouts. My eyes are getting old and somewhat knackered, so whilst E: D doesn't look quite as beautiful as 4K, it's good enough, and it's a compromise I was happy to make to be able to work again without straining to read everything. I just couldn't get on with the 4K screen for general use.