In line with Ozric just a quick look into how my braining works via an excerpt from a conversation in Fleetcomm Distant World chatter:
If plotting yourself along neutron highway, don't plot farther than 2kly at a go, and keep an eye on it every 500 or so. It's gonna try to cheat you on fuel and make you stop more than necessary. As long as you're in density you can push it out an extra neutron or three before a refuel by jumping to a neutron closer than the given fuel star. (this really only works in the inner density areas of the highway)
When you're a couple jumps from the end of that 1500-2000ly run, find another neutron 2000ly out and plot to it and continue.
This is using the in-game plotting tool of course. Not spansh.
Sure you CAN plot 9000ly but the in-game plotter gets confused after certain distances and will start giving you like 1 neutron, 1 fuel, 2 neutron, 1 fuel... It's trying to use the maximum fuel per jump rather than most efficient absolute fuel useage per tank.
Spansh has a limited data set as it pulls from known discovered neutrons. This leads to some gaps even along heavily traveled routes where it may just not know there are a bunch of neutrons in this untouched 100ly gap so it'll stop you short before it and jump you over it rather than letting you plow straight through it as you might be able to. (Just a hypothetical example but hopefully makes sense)
I like finding my own.
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Yes, I use only in-game tools meaning the route plotter but I've played with it enough I know its limits and that I still have to fiddle with it manually and make choices on the fly about what to do but getting to go 5-6 jumps in a row without messing about with copy-pasta is satisfying in its way.
Even with my 4:19:16, I thought the whole week after "I can take 20 off that for sub 4 easy, maybe a half hour." I was just exhausted from it and didn't want to try again. Long term in Buckyball, it's not gonna beat the computer algorithm for the most perfectly sequenced route; but, it would seem that stubborn old man intuition may still have a leg up on the average Spansh run.