I assume you're asking "how do combat players go about disrupting the actions of trading players who are all in trying to achieve the same goal?" Obviously combat pilots of BOTH sides in open will be equally able to disrupt the efforts trading pilots of BOTH sides who are also in open, but NEITHER will be able to combat the efforts of trading pilots in solo. Yes there will be pilots you can't shoot down, but that will be the same for BOTH sides. How do you combat trading pilots working for the other side in solo? Promote tranding pilots to also work for your team in solo. Traders in solo from BOTH sides will be equally targeted by NPC's, and combat pilots in open on BOTH sides will have equal numbers of opposing team members to shoot down. The result is not determined by "who gets to 50 first", it's determined by "which side has the most actions of ANY sort in ANY play mode by the time the action ends".
Why bother doing it?