Can confirm that Parallels works to run ED. It's not great, and planets render oddly and seem occasionally to cause crashes when I try land on raw surface bits, but overall the graphics are gorgeous on a high DPI display, and the game runs smoothly under most conditions. I've not tried heavy combat with it, but it shouldn't be too bad.
For reference, I'm on an M1 MacBook Pro running Parallels and an ARM distro of Windows.
EDIT: I should note here that it is well known that Macs do not "game" well, at least not in the sense that normal Windows-based gaming rigs do. I happen to prefer Mac for some things, and Windows for other things. However, I would personally recommend using custom or gaming-specific hardware, which usually means Windows. Since I cannot presently afford to own two PCs, and I am a man of science, this "Can it run on Mac?" challenge is quite entertaining for me!