If the question is literally credits per ton, then the answer is yes: find any rare, drive it 500LY, and sell it. With non rares, the answer's almost certainly no, since you're not going to find many commodities trading at 10K credits at all, much less 10K credits over the price you paid. Commodities just don't rise that high in price.
That's WHY everyone seems to be ducking your question -- it's not a meaningful question as phrased, so all the answers are "off topic" veering off in the direction of credits per hour, which is a more meaningful measure of a trade route's value.
That's WHY everyone seems to be ducking your question -- it's not a meaningful question as phrased, so all the answers are "off topic" veering off in the direction of credits per hour, which is a more meaningful measure of a trade route's value.