It does make me giggle how everyone all about the procedural generation as though it's a new thing and not something that was used thirty years ago to ram 8 galaxies into 28k of memory.
For a game on this scale, the generation will of course be needed to make those millions of stars/planets without having to have a hard disk the size of one, but personally, I'm just as interested in how it can be used to make the galaxy feel alive by making sure things like economies and missions aren't static.
There is probably going to be a certain amount of repetition with missions since there are only a few possibilities (go here, kill this, take this, bring it here) but that's fine as long as each time somebody does an action, it has consequences that change the state of the universe.
I really hope that we'll see possibilities such as say, a natural disaster on a major agricultural or trading centre have an effect on the whole sector.