If you don't use Steam, that game file verification is also a prime candidate

.
Other stuff support will tell you before even starting on your case:
- check that your graphics card drivers are up to date
- check that your OS is up to date
- check that your system fulfills the minimum requirements for ED (ok, that point is probably superfluous, but starnger things have been seen here...)
If it still happens, open a support ticket. Those guys and gals are usually on the ball.