Dirty! The dirtier the better.
seriously, my opinion - because it is only that, not saying it is some 10 commandments thing - is generally dirty drives are the overall winner for whatever overall build you are going for
faster cruise and faster boost = good for combat, good for running away, good for easier smuggling docking, etc. there really is no activity that the significantly faster thrust speeds of dirty v clean drives is not a better deal
better / faster pitch and yaw - here I can only go by subjective feel because have not actually tested the 360'degree normal space and SC pitch and yaw rates, but it does feel a bit like dirty drives are better than clean, but I can't see quite as much difference as the obvious delta between thrust speeds
if you want to min/max what clean gives you, it is still a nice mod but I think in most use cases of how most people play / build ships, dirty drives seem the 80-20 rule winner (e.g. If you don't know exactly and specifically why you are building with clean, you ought to just default to dirty)