Not easily.
Set a jump destination. Go look if it is the correct direction. If it is, follow the line out. Otherwise try a star in a different direction.
Or look up nebulae pictures on Google till you find it, then search the name on the Galaxy map. Nebulae names are searchable. The witch head nebulae is visible from lots of human space and looks very impressive, you can get there in about an hour with a good fsd.