Antimatter as a weapon might be the answer to getting a notch up on them. Just a thought.
I would of thought by our time line the dangerous aspects would have been controlled. It might be just the thing to catch them off guard. Shield it, drive it in the target and blam half the target disappears!Good idea, but if used incorrectly it will destroy yourself too!
Antimatter is dangerous if even the container is mishandled. I think a weaponized black hole would be easier, if we can find one in thargoid space to weaponize.
What source of antimatter will you use?