It really depends. If I have to go there over and over, the 2k LS at Furbaide are already pushing it. I wouldn't go much further than that, and I would ignore a trade goal if it's more than 3k out, unless the rewards are really good.
10k is out of the question, no matter how good.
If it's a combat goal I only have to cash in every now and then, it's different. I did Banki, after all. Four trips in total to the station. Bought a Sidewinder for that so I wouldn't get a massive integrity repair on my Clipper.
Is your poll for a trade or a combat community goal?