I fly a Python also, and it is true that you now REALLY have to know how to fly this ship. The AI is really really good at staying on your six, and the Python, while having a decent blue zone pitch, has a full speed pitch that's virtually non-existent. You absolute need to learn how to FA-Off Boost turn now with the Python if you want to even remotely have a chance to survive the new AI environment. Oh, and flying backwards. Or load up with lots of turrets and pile on the chaff and shield cell banks.
The Python is a great ship because of it's amazing internals and class 7 power distributor. But now, you need to look at more like a heavily armed trader rather than a true multirole.