I didnt bother with 1, as various things put me off. I picked up 2 and really enjoyed it. The character stuff and universe were fun. I did find the overall story and ending a bit rubbish, so was done with it at that point. The final boss and culmination of the story was silly as hell. Couldn't have given a monkeys about ME3 when it came round.
I'm looking forward to a fresh story in this and it looks fantastic.