Are you sure you got the win 10 64 bit version of software and drivers not the win7 -8,1 .
and have you tried to uninstall the software before installing again ?
Restart can also help after driver and software install.
I have the X52 stick with win10 pro 64 bit and newer had any problems,
Iam sure if you uninstall the software, install driver and software and do restart it will pop in...Good Luck !
Update: is the X52 Pro in the same usb slot as before ?
Some usb ports give more power than others.
http://www.saitek.com/uk/down/drivers.php
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Did you rub wax on your modem to make it faster?
Where does modem come into this ?, its really nice to have such a helpful CMDRs for those who are in need of good advice !