Once multiple hits happen, it can be a long time spent knocked out of commission, it is true!
Thanks ! Yes true, and that gets way more probable when you are solo in a spire site ! I played around there in this Anaconda build:
EDSY is a ship outfitting tool for Elite Dangerous
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This is a build with 6 Azimuth pre engineered MCs.
On the plus side, this shreds scouts in 5 seconds and eliminates Glaives without problems. I wanted to use it to farm Orthrus kills there, and it is able to kill an Orthrus without problems in principle. The downside is I always get shut down by the Banshee missiles and spend one third of my time tumbling around with all systems offline. All scouts and banshees all over the site focus on you in solo. So I get too less time to focus on the Orthrus spawns. Therfore I can only kill one of them per solo visit :-(.
The other good answer to the missiles (as above) is speed. With a Krait, around 300 m/s forward has been sufficient to evade their AOE(they act like airburst rounds, so will detonate a certain distance from your ship), and reversing at somewhere above 50 m/s will also do the trick. May of course depend on how long your ship is. I’m not sure an Anaconda or Corvette, for example, could avoid disruption by boosting through the missiles.
My Krait Mk 2 with 5 Azimuth MCs was unable to kill the Orthrus variants there, it was always just a little bit too slow to destroy them before they waked away. In the Anaconda build I posted above this was possible but I got the impression that large ships are just too big solo targets and you cannot outrun the missiles. Or I am doing something wrong

Maybe the spire sites are designed for groups of CMDRs rather than solo players, at least when you are playing in ships there (?).
Builds with multiple AX missile racks are not feasible there in practice in my opinion because you fumble around clumsily with them when dealing with local scouts and also with glaives / cyclopses on the way to the site. The Azimuth MCs really excel there.
I even tried killing Banshees with the 6 MCs but this was not possible. I just positioned myself closely in front of them and unloaded the Azimuth dakka-dakka at them, but they did not explode :-(( In my opinion, they are way too difficult to kill. Only with a Tormentor pistol from their downside , really ??