To make a good healthy colony I don't know if I am supposed to make it balanced (with a healthy mix of agriculture, industry, tech, commercial, security, government and population) or if it is better* to make the system heavily specialized. Or does it matter: does it make any difference to the player's game.
I don't know if placing two agricultural facilities in the same system is effectively better than two agricultural facilities in different systems.
* Stable system state, not going into famine, civil war, etc. and reasonable profit returns for the cmdr. Overall a good 'healthy' system.