In Skyrim you do make potions from plants and mushrooms (including fly amanita, which IRL is known for hallucinogenic properties—I don't recommend anyone to try, though, the damn thing may kill you, too) and it is very possible to make potions that have negative ("toxic") side effects. Some of these toxic potions grant the most alchemy exp and many are still useful for consumption because the negative effect is manageable.It's all about presentation. Skyrim is magic, potions are magic. Once you start talking about toxicity and deriving stuff from plants (as opposed to unicorn farts and fairy tears), it's not magic. Remove the mention of toxicity and its plant only derivation and you might get past the censors.
Not to mention mead, ale, wine, skooma and sleeping tree sap aka proto-hist sap, but now I'm veering awfully close to the Elder Scrolls lore rabbit hole. Let's just say that the rumor Ysolda dismissed as nonsense is actually fact, Clavicus Vile was involved in some grand shenanigans and the hist originate from beyond Mundus. Plus whatever the hell Kesh makes you inhale to communicate with Peryite
So, yeah, brewing frutexa tinctures and osseus elixirs would be perfectly fine and family-friendly even if unrefined versions will cause your character to lose all aiming accuracy while increasing sprinting distance by +100% for 30 seconds
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