No chance to run, no chance to fight back, no chance to progress at lower levels without running hundreds maybe thousands of missions for 2K-5K credits?
I too have tried running missions with decent amount (100K - 300K) of credits although with a much less expensive (T6) ship. Had some NPC assigned to kill me. (I managed to kill a very slow moving guy that immediately reappeared as soon as I went into super cruise?! I guess you do "Only Live Twice"). You can't escape them. Once you get the message someone is looking for you there is no jumping, star hopping, or maneuver that will get him off of you. Maybe if you are right next to your intended delivery point but I'm not sure that will work either. Tried running, his first pass took my shields completely, boost did not take me out of range, second pass took engines and any chance to run and then a destroyed ship. Happened three times in a row with loss of all cargo. The one time I managed to get to a friendly system with him right behind me he still could not be taken down with two federal ships and me trying. He just jumped out and came back when I went into super-cruise. Lost around a million credits in about 10 minutes in those three attempts. At the amounts per run you can make that equates to several hours and that is difficult for me to love. I would love having a chance, at least at lower levels, to progress to the tougher ones. I was trying to run the Trade Data/Black Box missions until four (4) ships started showing up to stop me. Again, no chance. At this point I don't think I would dare attempt one of the assassination or elimination missions. I doubt I would get a shot off.
It would be nice to have some higher paying low end missions or less interdictions at lower levels. Most of the time is spent flying around open space. As nice as that is it gets very monotonous. Throwing in a couple interdictions makes it interesting but, when you are flying a ship that can not fight back due to weak weapons and low maneuverability, and your ability to run is removed, that makes it frustrating. Add to that the incredible loss of credits at the lower levels along with the cargo and the cost of same and you feel like you are starting over all the time.
I'm not ready to give up on it quite yet. I do think it is a little unbalanced in the beginning. Watched tons of videos (most outdated now), read different posts (equally outdated). Problem with most is they are using ships that you, as a beginner, do not have access to. Some of the suggestions and methods won't work with the early ships. Still useful information but not entirely able to be implemented.
Then there are the training missions. You are given ships to "train" with that you do not have immediate (maybe not for a year) access to in game. Sort of like training with a P51 Mustang against WW1 biplanes then being issued a biplane to fight an F4 Phantom. It does not really give you any idea of what it is going to be like. The AI on the training missions is much weaker than what you run into. Would be nice to have a "training area" that allows you to use the ship you have or are thinking about purchasing to "test drive" without the loss of credits. At least in solo mode you could get an idea what you will be facing. If you go open all bets would be off but you would know that ahead of time.
Oh and I'm running in solo play. I wouldn't attempt open. Given my experience so far I may never. Too much loss for too little return. We'll see though.