There are some great VR tweaking threads in these forums. Many were started a long time ago but still have recent contributions.
I have a list of some of my favourites in the "VR Section" (near the bottom) over here ...
Alec's-best-of-the-forum-(and-elsewhere)-thread
To cut a long story short tho, the first thing you should probably do is install drkaii's excellent "EDProfiler" utility. This is a utility which allows you to maintain various different graphic profiles for ED (each profile contains all the graphics settings, keybindings
*1 and HUD colours that you've configured for that profile). Apart from anything else this is brilliant for having separate VR and non-VR profiles that you can switch between at the press of a button prior to launching the game. Another good reason to use EDProfiler is because you'll see a lot of people sharing their VR settings by posting a screenshot of the EDProfiler window.
*1 which will solve your keybindings problem!
For example, here's mine from some time back ...
Like you I now have a GTX 1080 (plus an i5 4690k) and after much tinkering have arrived at some settings I'm really happy with. I don't have an up to date EDProfiler screenshot but basically a good starting point for you would be ...
- turn Bloom, Blur, DoF, Ambient Occlusion and Anti-Aliasing off (actually scratch that last one, I'm pretty sure I use FXAA these days - not at my PC to check right now)
- set Shadow Quality to High (this is a matter of personal taste - Shadows is a fairly GPU intensive operation so this comes at a cost ... but I like shadows)
- set Super Sampling (SS) to 1.0
- set HMD Quality to 1.25
- set all the other settings to their maximum values
- wind down the gamma a fair bit (until space is basically black)
- pick a better HUD colour (if you're using EDProfiler then drkaii's "Spiritual Teal" is pretty good)
With those settings and your hardware things should look pretty good (depending on your VR expectations ... there's no getting around the fact that the hardware screen resolution is fundamentally poorer than a 1920x1080 monitor) and you should get 90fps most of the time.
On the subject of fps, by default you will have Oculus ASW (Asynchronous Space Warp) turned on every time you start the game. ASW spots when your game isn't getting 90fps, limits it to 45fps and creates in-between frames to simulate 90fps. If you press Ctrl+F you'll see an fps display on your monitor's screen (you can peer at this down the Oculus nose gap). With ASW on it will always be either 90fps or 45fps. To see the true framerate you're getting you can turn ASW off by pressing Ctrl+NumPad-1.
Good luck! VR is awesome and it's worth spending a bit of time tinkering to get the best out of it. It's worth noting however that some people are simply unable to get over the fundamentally lower resolution of the 1st gen VR hardware and do end up selling their VR kit. Personally I think this is great shame but ultimately it's up to you. For what it's worth what I tend to do is play some of the time in VR (when I just want to get that absolutely awesome sensation of actually being IN the game) and other times on the monitor (when I want to capture screenshots, or video, or look at other things on my screen at the same time or to just savour the glorious hi-res graphics). Unlike the "you can never go back" crowd I'm now entirely happy with this situation and have zero regrets about buying into VR when I did.