An experiment involving a few million hamsters and a rather enterprising cat is what led to the eventual discovery of the mechanics of a frame shift drive.
Edit: Really, W ang, an incredibly common surname can't be posted on a forum because some adolescent might think 'w ang, hur hur hur'. @#$)*(@#) stupid humans.
Thrusters use the same amount of fuel all the time (yeah, I know) but so do sensors, and shields, and your cargo hatch... This is why I power down everything I don't need and use FA-off to power down my thrusters when travelling any distance non-frameshifted. Fuel savings are huge - like, a quarter of a tonne per hour.