Audio can really draw you into a game, and ruin it with its absence. I remember in X3: Terran Conflict that there were some sectors that were lost, literally in the middle of nowhere. It's been a while but when you jump to one of these hidden sectors it's almost entirely black, and all you can hear is some kind of static like sounds, perhaps radio emissions from distant stars. It reinforced the impression you had just jumped to some where desolate and very, very far away from anything you would call home.