Just about all of Horsehead is permit locked. There's a spot here and there in Bernard's loop that's reachable but for the most part, no joy there.
If you're in the galaxy map and search for COL 70, you'll see "Requires unknown permit" for everything with that designation. "COL" everything else appears to be open, so there's something coming in 70. I feel it might be the two nebula areas that get released first, since there appear to be "things pointing that way" in the ruins (based on what I've read so far).
COL 121 and COL 97 Sectors are also shut down. If I remember correctly from CNE, both COL 70 and COL 121 were locked down when 1.6 was released, they were open before that. I'm not sure about COL 97, when that was locked. But I agree with you that region of the galaxy, definitely has something of interest.