My opinion, for what it is worth, is that the only players you will find in the core systems or hubs will be newbies (poor things) and those who want to play space cowboys and indians as their raison d'etre. I think it is likely that a majority will very quickly head away from the core systems for one of two reasons.
1) To explore... that pretty much explains itself.
2) To find (either individually or as a co-operative) a group of systems where they can trade, do missions and generally play the game as they want without having to keep looking over their shoulder all the time for players who want to kill you 'just because'.
I think it would be rather a shame if, after being given a whole galaxy to wander around in, people decide to huddle together in one teeny, tiny itsy bitsy little part of it. Guys, the galaxy is huge... no, bigger than that.... Here. I pulled this of Wikipedia:
"As a guide to the relative physical scale of the Milky Way, if it were reduced to 100m in diameter, the Solar System, including the hypothesized Oort cloud, would be no more than 1mm in width, about the size of a grain of sand. The nearest star, Proxima Centauri, would be 4.2 mm distant.[nb 3]
Alternatively visualized, if the Solar System out to Pluto were the size of a US quarter (25mm in diameter), the Milky Way would have a diameter of 2,000 kilometres."
I don't know about you but I want to be out there.