Back around launch I used to explore in an armed ship because there were NPC interdictions all over the galaxy. Honestly, I almost always just ran from them, but it was a bit of an affectation, at the same time. These days, I carry a heat sink launcher and nothing else.
There has been some talk in the Dead End Circumnavigation Expedition about carrying one railgun, engineered by Tod "The Blaster" to have the Plasma Slug side effect. This makes ammunition come out of your fuel tank, which makes it borderline useful for fine tuning the amount of fuel you're carrying in order to manage jumps at the ragged edge of your jump range.
That said, there are Thargoids out there, at least around the Pleiades. Who's to say we won't run into more hostiles somewhere. FDev have hinted at it. Still, until someone encounters something that changes my mind, my money is on running from trouble.