I honestly believe in my kill order to minimise incoming damage. Taking out the Annie first will mean that all 6 ships are up until you can get it down. If you are amazing at being evasive, then this might indeed be the way to go, but the thing to remember is that the Anaconda's DEFENSE is better than its ATTACK, so I feel that literally reducing the number and more importantly SIZE of the hardpoints firing at you is really important. Therefore I take the targets out based on a gut feeling equation of number and size of hardpoints vs maneuverability.
Therefore, FDL first, you can get it down quickly, and that's 1 huge and 4 medium hardpoints out of the game straight away. Next the Asp, again it's down very quickly, VERY quickly with the dakka dakka setup, its hull just melts in one volley. With those two down, you have almost halved the number of guns on you. The vulture is very maneuverable, so it's two large hardpoints get weighted higher and is the next target (you can swap it with the Asp if you want, but hte Asps often have 6 gimbals, if explorers). You can then think about tanking the cobra and the viper while you take out the annie. Or, if you're good at lining up small ships, take them out quick and then you're left with a one on one with the Annie.
You know, here for literally the first time in this game we see the sort of decision-taking that is second-nature to a trustworthy PvP-wing shot-caller being applied to solo PvE.
Considerations of relative target threat, TTK and so on that PvP players like Nyxi excelled at, becoming relevant to the single-player experience.
I applaud, and feel this underlines my point that Frontier are making progress.