I have tried many variations, but found the '4 pulses/1 huge cannon' to lack the necessary punch for such a ship as the FDL.
So I find that having a class 3 gimballed beam laser on the huge hardpoint, coupled with two class 2 gimballed beam lasers on the outer hardpoints, to be ideal for stripping shields; while having either gimballed or fixed class 2 cannons on the central hardpoints ideal for targeting subsystems and destroying the hull. This setup also allows you to manage the heat build-up too by alternating between lasers and cannons.
Alternatively, use the class 2 hardpoints as above and add in a class 4 weapon to the huge hardpoint, such as a fixed or gimballed cannon or a fixed plasma accelerator (class 4 is expensive but worth it, IMHO). The cannon will obviously be better against the hull, whereas the PA will be devastating to shields - assuming you can hit anything with it! I recommend getting up close and using it as your opening salvo...
