With SF my interest was kicked off by Arthur C Clarke's books, particularly "The City and the Stars", and the final novel version of 2001. Easy to read when you're young, but the ideas are challenging and thought-provoking, even now I'm nearly 50.
Got into Asimov "Foundation" and Niven (still can't understand why no one has tried to film "Mote in Gods Eye"). Currently enjoying some of Stephen Baxter's later SF novels. Still very much attracted to hard SF, and hope to start writing some soon.
TV wise, I really enjoyed Dr Who, once I was old enough to stop running upstairs when the theme music started, and have enjoyed Fringe, Firefly, and the original Prisoner. I've always found SF films disappointing, they rarely rise above the "Cowboys with Lasers" level, though 2001, Blade Runner, and Alien are all good.
Gamewise I found "Alpha Centauri" an easy winner, such a rich storyline and so easy to adapt to differing play styles. Oh, and I enjoyed a thing called "Elite" as well, don't know if anyone has heard of that.
Cheers, Phos.