As someone who has flown a Python ~9k LY out to the Eta Carina nebula complex and back, with a 21.2LY jump range, I have a couple of observations that I hope may help you. Firstly, it's not a problem to go long distances with this kind of jump range but you may have to pick your route very carefully if you want to cross the spiral arms or go where the star density gets low. You take longer to get somewhere if you're using fastest route planning but the Python can take a class 6 fuel scoop which fills your tank up quickly. It is expensive, however: I brought mine back to dock undamaged but with the integrity (wear and tear) down to 40%. I think it cost me about 1.6 million to repair that. As for the handling, the Python is slower to turn than the Asp in supercruise but not painfully so and the view is reasonable, similar in some respects to the Cobra. I also felt very safe coming home with my valuable exploration data, which for me was a big plus: I had previously been interdicted by an Elite NPC Viper two jumps away from Tsu for the community goal there when in my Asp and lost my shield and nearly 20% of my hull before I could hyperspace away. Exploration is a test of risk management, so find a good balance that works for you - fly safe!