So you
are talking about putting oneself in harms way, and looking for ways to reduce the PvE/PvP gap.
If you want to go somewhere where there are lots of people, you are going to find lots of them are using the best equipment (for whatever their aim is). If you have the best equipment for your aim, you are much more likely to have any hostile encounter be decided by skill & experience than loadout or ship choice.
So if you are going to try going there for the first time in Open (and therefore lack the experience & probably skill), you can mitigate that risk by doing that in a 'safe' ship. Something very, very fast, or very, very tanky.
Or another way to mitigate the risk might be to go in a ship you are very familiar with, the one you can speed dock because you know just how much it drifts, how quickly you can boost turn it around the rocks in a RES.
One you become a bit more comfortable with just being around lots of other players, and feel more able to identify which ones are an actual threat, you can start to mitigate less, optimise a bit more for carrying cargo or whatever. Eventually, with experience you will reach a point where you are reasonably satisfied that you can not only survive, but achieve objectives. Any hostile players can be treated simply as extra tough NPCs if you like, but unlike NPCs human players can be interacted with in far more ways than just shooting at them, you can gain allies & make friends, or just swap stories
The first step is just to give it a try for yourself, see how you get on (just as TobiasFuzz describes).