That's what I get for reading only half the post jesus
Anyway, the a stripped python with D rated everything and A rated FSD has decent range so you could use it do replace your Asp but in all honesty the Asp is just better for long range trading simply because the Python's range goes down to ~15LY when fully loaded
This build has a 5A power plant because better thermal efficiency. Fuel scoop for virtually infinite range and mine launchers because you're gonna get interdicted almost every jump, not even kidding. Mine launchers are actually pretty powerful now by the way, just look at this.
All in all, you're looking at over 80M, unless you visit space chinaman (Li-Yong Rui) for 15% discounts.
The reason I'm upgrading to the python is becuase i can carry atleast double the amount of cargo, the trading I am doing are long range missions ~400lys. Granted it may take longer to jump that far with a bigger ship, I can carry much more cargo and effectivly double the profit per trip. At about 15ly jump range on the python you're citing, i have more than half the jump range of the ASP, but with atleast double the cargo. Based on those numbers, I believe I will be making more per hour with the python.