This project looks like The Expanse meets Rimworld (or Prison Architect). Focus is less on "colony sim" and more on "space combat, cargo and exploration" but still has a lot of "base / ship building" features.
store.steampowered.com
This is still in (quite solid) alpha.
Here's the latest dev update:
Source: https://www.youtube.com/watch?v=cRRo9zig9VY
Really looks awesome. That space combat looks very appropriately brutal. I'll certainly spend a lot of time on this...

The Last Starship on Steam
Introversion Software, the indie legends behind Prison Architect, Darwinia, DEFCON and Uplink, present to you the broken, unfinished and bug filled Alpha of The Last Starship. Pick a ship hull, kit her out with engines, life-support, sensors and rail guns and start your galactic adventure!
This is still in (quite solid) alpha.
Here's the latest dev update:
Really looks awesome. That space combat looks very appropriately brutal. I'll certainly spend a lot of time on this...