I personally have reservations about some of the hyperbole around colonisation. It kind of reminds me of the fan uproar of <spoiler> killing James Bond at the end of No Time to Die </spoiler>. People threw their arms in the air and loudly proclaimed "We can't have any more Bond movies because you've killed him". I viewed it differently, and asked why when Casino Royale in 2006 showed Bond gaining 00 status for the first time absolutely nobody threw their arms in the air and shouted "How can you show Bond's first ever mission now, does this mean the previous 20 films never happened!?"
Colonia didn't ruin the game, the Colonia bridge didn't ruin the game, fleet carriers didn't ruin exploration, and colonising the galaxy isn't going to ruin the game either, especially given how few colonies would end up being out there comparable to the sheer volume of available systems we could build in.
For anybody on the Sag A* / Beagle Point route then, fine, it's fair. But there are far more, and far far better parts of the galaxy to explore that wouldn't be touched at all, and we can say this with considerable certainty.