I have reviewed multiple selectable commodities in the past when the Planner was introduced, but the most profitable way is to transport only the commodity with the highest profit (as like the Route Finder is doing it).
Since an important feature is being reworked, I wanted to give my thoughts on it, as a BGS player.
While the most profitable path is to simply fill your cargo with the most profitable commodity, based on Goemon's research on trading for influence there is benefit in having more than 1 type of commodity, ideally 4 or 5 for large pads. So it would be very helpful BGS-wise to find routes that have multiple commodities for profitable trade.
A second point of feedback I would like to give, is that trading for a loss is a way to attack a faction. Finding those "loss routes" could be very helpful for BGS players too.
I like how the BGS adds these complexities to trading, but I don't know how complicated it would be to incorporate those changes so I wanted to at least point out why they could be useful for your consideration. Anyway, thank you for your continued support on this amazing ED tool (personally my favorite)!