I watched a youtube by D2EA and he spent 2 hours looking for Pharmaceutical Isolators and didn't find any, and only found one HGE in Outbreak.
Yea, right... that doesnt mean PI are not spawning, it just means D2EA need to do his homework better
check this older post of mine:
Newcomer / Intro - Learning about collecting manufactured
I think I see what you're saying. What I thought was a bug is probably a feature. When I set both population sliders to let's say top = 7/10 and then bottom = 10/10, then I get this funny problem. But it sounds like I need to set them differently and I will see the different size bubble icons...
or this one