I get concerned by how often people mention that they enjoy annoying other players.
Is posting your experience in a forum and others commenting on it really "unsolicited"?
Griefers are part of the game. It's their fun to blow up unsuspecting players for nothing. It's also part of the game to make life difficult for them. You can play as a white knight, a policeman or a nasty yappy dog that keeps biting their ankles - nothing wrong with that, and it's exactly what I am doing at the moment.
Where I am, there's a continuous stream of harmless and mostly harmless commanders full of hope as they fly in to get their ships upgraded, but from time to time there are one or more players that want to give them disappointment by blowing them up. My role is to ensure that ,as far as possible, the hopes of the innocent players are fulfilled.
Contrary to what has been said, you don't need a fully engineered combat ship to chase these bad guys away. All you need is a fast Sidewinder with a 2A FSD interdictor. Weapons aren't needed, neither are shields. performanced enhanced thrusters help a lot. You interdict the bad guys, then boost away in silent running, go back to SC and repeat. Even if you mess up, the rebuy cost is so low that the guy that got you probably paid more for ammo, so pay your rebuy cost and go and get them again and again until they leave or block you. By blocking you, they cut down the chance of interacting with any players that come into your instance, which will reduce their opportunities to grief, so either way you win.
Another way to get them is when they're hanging around a player magnet in normal space. You get a shieldless Sidewinder with a long-range beam laser with thermal vent, long range sensors and performance enhanced thrusters. You drop into the instance and move out to about 10km. You now have two choices: Firstly, you can choose a target, engage silent running, go in and blast them from about 5 to 6km. That won't do any damage, but it will register on their radar as incoming fire. They probably won't be able to see you, but when they turn, boost at right angles and repeat or boost away out of range again, then repeat. Secondly, you can save the good guys when they get attacked by one of the griefers by charging in and getting the griefer from behind, which at least at first makes them panic and turn around, then you run away. That gives the good guy victim a chance to escape. It's great fun running the gauntlet of the griefers gang. There are often 4 or more in the gang, so you need to be careful about which direction you approach and escape. watch out for fast ships in their gang, like Imperial Courriers. Silent running will be your friend if you can get enough range to disappear.