Yup. I engineered two FSD's to the max of G5 last night.
The first took 5 rolls, which is reasonable. The very next took 12, which is just silly. 6 of those 12 were tiny increments right at the very top of the grade. Just pure bullpoop.
I'd already spent about 4 hours collecting chemical manipulators at Dav's Hope previously, and a similar amount of time in a Distribution centre scanning wakes for DWE's.
I ran out of them twice last night.
You'd be better off collecting pharmaceutical isolators and trading down to chemical manipulators. DWEs you'll still have to grind.