Possibly, saying that though, with the obvious less-than-harmonious reaction of 'goid tech to guardian tech, for all we know we will be ground down to the brink of defeat by insect overlords who don't even give us the time of day and then "deus ex guardians" will occur.
This would throw -what will by then be- the established human/alien interaction clean out of the window. They have foreshadowed pretty heavily when it comes to them, dumping all kinds of lore into our eagerly waiting brain-boxes so it seems likely something to do with them (guardians or their relics/remnants) will rear it's head at some point.
You have to admit, that drives a much longer ranged story arc (and probably a more interesting one) and provides far more room for future intrigue and mystery than something along the lines of "then they all had a brew and a chat and started to get along", which in my opinion leads to a caged end result and stagnant story telling (just my opinion mind you, I can certainly see how others would disagree).
I think it's pretty safe to say that the situation with the Oresrians and Klaxians means the 'brew -> chat -> get along' isn't going to happen, regardless of what we (cmdrs and humanity) do.
RP style because why not!

:
My fellow commanders, we must face reality. War has become unavoidable.
If we ally ourselves with the Oresrians we will be in conflict with the Klaxians.
If we oppose the Oresrians then we are immediately in conflict with them and are likely to end up in conflict with the Klaxians subsequently at which point we will have helped eridacate our only potential ally.
If we remain impartial with the Oresrians then their human shield plan comes to fruition and we are left less well able to defend ourselves.
Our best strategy would be to remove ourselves from the path of conflict. However efforts to enable this option have been undermined from within by parties who have considered nothing beyond their own selfish agendas.
Although we do not yet feel its cold fingers, nevertheless, winter is upon us.