Data point - using the 22.5.2 drivers with a RADEON VII (16GB) - older card than the 6000 series but the floating point unit makes it worthwhile since my research machine doubles as my gaming machine.
Upon loading after updating the driver
Launched Odyssey
85 seconds for generating first part of shaders
80 seconds to generate the planetary shaders
Let station, flew to planet, approached and landed and took off a couple of times - no issues noted.
Graphic settings are set to ULTRA and SAM disabled (actually not supported with the Threadripper 2950) no other changes made from 22.5.1 settings. I don't have any of the Adrenalin gaming features enabled.
Typically I see about 58-72 FPS at Ultra in pretty much all parts of the game with sometimes a 10 FPS drop at ground stations with about 68% GPU utilization. My main monitor (Dell 3415) is locked at 60 Hz so no real need for much higher.
I am not sure how closely the Radeon VII (which is a 2nd gen Vega chipset) is to the RX 6000 series to tell if they would share any architectural bugs related to Odyssey. If there is any testing I can do to help pinpoint this let me know. I have an 6950 card I was planning for a different system I can swap in.
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System
TR 2950, Gigabyte Aorus Xtreme MB (F5), 128GB main RAM, Radeon VII, Windows 11 Education on its own NVME drive and ED on a separate NVME drive.