Probably two high end interceptors at the same time, with both large swarms and the interceptors attacking you, maybe in missile mode? The pro ax folks focus heavily on damage avoidance and reduction because the max potential dps of the big interceptors with their full swarms is more than any ship can take for more than a few seconds, if it’s the absolute worst case with the horrific swarm damage.I have faced-off against a solo Medusa before. It was nowhere close to delivering the kind of DPS needed to trash my ship that fast, even with a bunch of mates. I reckon it was about three maybe four seconds from "fine and dandy" to "utterly f****d".
Still confused
Also, you can sometimes get random module failure from xeno fire; they normally come back on after a few seconds, but I’m wondering if they managed to randomly hit your power plant and blow the ship? They tend to do very heavy module damage and interfere with modules a lot. My life support keeps temporarily failing mid-fight, for instance - worrying the first time but you get used to it
Best option when you get the “interceptors coming in hot” warning is to boost and fa-off, while the shutdown field happens, so you’re not the one they go for. This is another benefit of having so many sacrificial npcs - I mean, highly esteemed comrades in arms - in the ax conflict zones