If you want to find unexplored systems on the way to colonia or anywhere else. Plot to a target system a few hundred LY to the side of it, then go up or down 500LY before going in that direction. If you do that, I'd bet that 50% of all systems you go through will be undiscovered. Most people plot a direct route from a to b, so they all go through the same systems. You don't have to deviate far from that line to be in new space.What I did was head towards Colonia, the other side of the Sagittarius Gap, roughly northeast from Sol (The Orion Spur). Head for the Scutum-Sagittarii Conflux, when you pop into a system and the star doesn't show up on your HUD for 3 to 5 seconds, it's an undiscovered system, honk it with your discovery scanner. I always move around the star, line up with my next jump vector taking my speed up to 5x the speed of light.
I do that to make sure there aren't any planets hidden behind the main (Closest) star.
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EDSM - Elite Dangerous Star Map
The Galactic Positioning System of Elite: Dangerous at your service.www.edsm.net
It reminds me of when I go sailing. In the old days, you'd hardly see another boat, but now that everyone uses GPS and start and finish with the same waypoints, and use auto steering locked to the GPS route, you have to take avoiding action for nearly every other boat that you see. Basically, you have the sea to yourself for hours, but every time you see another boat, you have to take avoiding action, unless you start half a mile to the side of your start waypoint and plot a point half a mile to the side of the finish waypoint (normally a port), then you can relax and let the boat do its thing.