For me the whole mission board locks up immediately. I only get some corrupted, overzized graphics of parts of the menus with no text or infos and lockup.
Have you logged out and in again? Might be that the very first faction has no missions you can accept, which would lead ot the soft lock. Logging out and in again could flip the board, changing that.
I'm trying that tomorrow, gotta sleep. Long day.
I really, really, REALLY like this game. It keeps drawing me back like a moth to an open flame. Otherwise, I wouldn't be complaining about the slew of glaringly obvious bugs released with the latest fix, I'd simply delete the game and move on. As it is? Thousands of hours spent, and hours WELL spent, mind. I cannot wait till tomorrow, until after work, household chores, and having taken care of my kids. Time to play ED again, then.