Like most trading tools these day you are missing the most profitable trades that PP introduced.
Stations that Buy and Sell the same item only show numbers for Supply. Demand is empty and thus all trade tools think that they can not sell this item, but you can.
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As an example: My favorite trading tool, when set to "show me the most profitable trade between two stations", tells me to trade in coffee/tea one way and land enrichment systems the other way- for a trip total of 600cr/t.
However, I am trading Imperial Slaves for over 3000cr /t one way (the sell system can sell and buy the same item, but only show supply numbers) and the mentioned "land enrichment systems" the other way. All trading tools that I have tested miss this trade!
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Before PP this system only had Supply of Imp. Slaves- you could not sell to the system. Now due to PP passive effects, you can sell Imp. Slaves to the system, but as mentioned earlier, the demand for imp. slaves is empty and thus all trading tools think you cant sell to the system- but sell you can. I have made over 50mil on this trade the last couple of days.
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This is only one example, but I have been in a lot more system where the same thing apply- since now I have to manually hunt for the best trade route and basically is back to pen and paper again.
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Edit: I am not sure if trading tools miss this trade due to empty demand or if they get confused when you can sell and buy the same item, but one thing is for sure that all tools I have tested do miss this trade.